Publications
Featured Publications
2023
Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell Metab. 2023 Apr 12:S1550-4131(23)00123-7. doi: 10.1016/j.cmet.2023.03.018. Epub ahead of print. PMID: 37075753.
Suzzi S, Croese T, Ravid A, Gold O, Clark AR, Medina S, Kitsberg D, Adam M, Vernon KA, Kohnert E, Shapira I, Malitsky S, Itkin M, Brandis A, Mehlman T, Salame TM, Colaiuta SP, Cahalon L, Slyper M, Greka A, Habib N, Schwartz M. N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer's disease mouse model. Nat Commun. 2023 Mar 9;14(1):1293. doi: 10.1038/s41467-023-36759-8. PMID: 36894557; PMCID: PMC9998639.
Yoon SH, Meyer MB, Arevalo Rivas C, Tekguc M, Zhang C, Wang JS, Castro Andrade CD, Strauss KE, Sato T, Benkusky N, Lee SM, Berdeaux R, Foretz M, Sundberg TB, Xavier RJ, Adelmann CH, Brooks DJ, Anselmo A, Sadreyev RI, Rosales IA, Fisher DE, Gupta N, Morizane R, Greka A, Pike JW, Mannstadt M, Wein MN. A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis. J Clin Invest. 2023 Mar 2:e163627. doi: 10.1172/JCI163627. Epub ahead of print. PMID: 36862513.
Shaw JL, Pablo JL, Greka A. Mechanisms of Protein Trafficking and Quality Control in the Kidney and Beyond. Annu Rev Physiol. 2023 Feb 10;85:407-423. doi: 10.1146/annurev-physiol-031522-100639. PMID: 36763970.
2022
Eraslan G, Drokhlyansky E, Anand S, Fiskin E, Subramanian A, Slyper M, Wang J, Van Wittenberghe N, Rouhana JM, Waldman J, Ashenberg O, Lek M, Dionne D, Win TS, Cuoco MS, Kuksenko O, Tsankov AM, Branton PA, Marshall JL, Greka A, Getz G, Segrè AV, Aguet F, Rozenblatt-Rosen O, Ardlie KG, Regev A. Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function. Science. 2022 May 13;376(6594):eabl4290. doi: 10.1126/science.abl4290. Epub 2022 May 13. PMID: 35549429.
Sharma S, Pablo JL, Tolentino KT, Gallegos W, Hinman J, Beninato M, Asche M, Greka A, Hopkins CR. Further exploration of the benzimidazole scaffold as TRPC5 inhibitors: identification of 1-alkyl-2-(pyrrolidin-1-yl)-1H-benzo[d]imidazoles as potent and selective inhibitors. ChemMedChem. 2022 May 12. doi: 10.1002/cmdc.202200151. Epub ahead of print. PMID: 35557491.
Marshall JL, Noel T, Wang QS, Chen H, Murray E, Subramanian A, Vernon KA, Bazua-Valenti S, Liguori K, Keller K, Stickels RR, McBean B, Heneghan RM, Weins A, Macosko EZ, Chen F, Greka A. High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways. iScience. 2022 Mar 16;25(4):104097. doi: 10.1016/j.isci.2022.104097. PMID: 35372810; PMCID: PMC8971939.
2021
Clark AR, Marshall J, Zhou Y, Montesinos MS, Chen H, Nguyen L, Chen F, Greka A. Single-Cell Transcriptomics Reveal Disrupted Kidney Filter Cell-Cell Interactions after Early and Selective Podocyte Injury. Am J Pathol. 2021 Nov 30:S0002-9440(21)00513-7. doi: 10.1016/j.ajpath.2021.11.004. Epub ahead of print. PMID: 34861215.
Watts A, Keller K, Lerner G, Rosales I, Collins A, Sekulic M, Waikar S, Chandraker A, Riella L, Alexander M, Troost J, Chen J, Fermin D, Yee J, Sampson M, Beck L, Henderson J, Greka A, Rennke H, Weins A. Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology. J Am Soc Nephrol. 2021 Nov 3:ASN.2021060794. doi: 10.1681/ASN.2021060794. Epub ahead of print. PMID: 34732507.
Zhou Y, Kim C, Pablo JLB, Zhang F, Jung JY, Xiao L, Bazua-Valenti S, Emani M, Hopkins CR, Weins A, Greka A. TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models. Front Med (Lausanne). 2021 Sep 21;8:721865. doi:10.3389/fmed.2021.721865. PMID: 34621762; PMCID: PMC8490698.
Yoon H, Shaw JL, Haigis MC, Greka A. Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity. Mol Cell. 2021 Sep 16;81(18):3708-3730. doi: 10.1016/j.molcel.2021.08.027. PMID: 34547235.
Ningoo M, Plant LD, Greka A, Logothetis DE. PIP2 regulation of TRPC5 channel activation and desensitization. J Biol Chem. 2021 Apr 29; 296:100726. doi: 10.1016/j.jbc.2021.100726. Online ahead of print. PMID: 33933453.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Gasdermin D pore structure reveals preferential release of mature interleukin-1. Nature. 2021 Apr 21. doi: 10.1038/s41586-021-03478-3. Epub ahead of print. PMID: 33883744.
Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Triglia ET, Ansari M, Cai P, Lin B, Buchanan J, Chen S, Shu J, Haber AL, Chung H, Montoro DT, Adams T, Aliee H, Allon SJ, Andrusivova Z, Angelidis I, Ashenberg O, Bassler K, Bécavin C, Benhar I, Bergenstråhle J, Bergenstråhle L, Bolt L, Braun E, Bui LT, Callori S, Chaffin M, Chichelnitskiy E, Chiou J, Conlon TM, Cuoco MS, Cuomo ASE, Deprez M, Duclos G, Fine D, Fischer DS, Ghazanfar S, Gillich A, Giotti B, Gould J, Guo M, Gutierrez AJ, Habermann AC, Harvey T, He P, Hou X, Hu L, Hu Y, Jaiswal A, Ji L, Jiang P, Kapellos TS, Kuo CS, Larsson L, Leney-Greene MA, Lim K, Litviňuková M, Ludwig LS, Lukassen S, Luo W, Maatz H, Madissoon E, Mamanova L, Manakongtreecheep K, Leroy S, Mayr CH, Mbano IM, McAdams AM, Nabhan AN, Nyquist SK, Penland L, Poirion OB, Poli S, Qi C, Queen R, Reichart D, Rosas I, Schupp JC, Shea CV, Shi X, Sinha R, Sit RV, Slowikowski K, Slyper M, Smith NP, Sountoulidis A, Strunz M, Sullivan TB, Sun D, Talavera-López C, Tan P, Tantivit J, Travaglini KJ, Tucker NR, Vernon KA, Wadsworth MH, Waldman J, Wang X, Xu K, Yan W, Zhao W, Ziegler CGK; NHLBI LungMap Consortium; Human Cell Atlas Lung Biological Network. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021 Mar;27(3):546-559. doi: 10.1038/s41591-020-01227-z. Epub 2021 Mar 2. PMID: 33654293.
Chamberlain BT, Vincent M, Nafie J, Müller P, Greka A, Wagner FF. Multigram Preparation of BRD4780 Enantiomers and Assignment of Absolute Stereochemistry. J Org Chem. 2021 Mar 5;86(5):4281-4289. doi: 10.1021/acs.joc.0c02520. Epub 2021 Feb 22. PMID: 33618515.
Sidhom EH, Kim C, Kost-Alimova M, Ting MT, Keller K, Avila-Pacheco J, Watts AJ, Vernon KA, Marshall JL, Reyes-Bricio E, Racette M, Wieder N, Kleiner G, Grinkevich EJ, Chen F, Weins A, Clish CB, Shaw JL, Quinzii CM, Greka A. Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease. J Clin Invest. 2021 Mar 1;131(5):e141380. doi: 10.1172/JCI141380. PMID: 33444290; PMCID: PMC7919729.
2020
Kost-Alimova M, Sidhom EH, Satyam A, Chamberlain BT, Dvela-Levitt M, Melanson M, Alper SL, Santos J, Gutierrez J, Subramanian A, Byrne PJ, Grinkevich E, Reyes-Bricio E, Kim C, Clark AR, Watts AJB, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A. A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury. Cell Rep Med. 2020 Oct 29;1(8):100137. doi: 10.1016/j.xcrm.2020.100137. PMID: 33294858; PMCID: PMC7691435.
Marshall JL, Doughty BR, Subramanian V, Guckelberger P, Wang Q, Chen LM, Rodriques SG, Zhang K, Fulco CP, Nasser J, Grinkevich EJ, Noel T, Mangiameli S, Bergman DT, Greka A, Lander ES, Chen F, Engreitz JM. HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33404-33413. doi: 10.1073/pnas.2010738117. Epub 2020 Dec 21. PMID: 33376219; PMCID: PMC7776864.
Dvela-Levitt M, Shaw JL, Greka A. A Rare Kidney Disease To Cure Them All? Towards Mechanism-Based Therapies for Proteinopathies. Trends Mol Med. 2021 Apr;27(4):394-409. doi: 10.1016/j.molmed.2020.11.008. Epub 2020 Dec 16. PMID: 33341352.
Olinger E, Hofmann P, Kidd K, Dufour I, Belge H, Schaeffer C, Kipp A, Bonny O, Deltas C, Demoulin N, Fehr T, Fuster DG, Gale DP, Goffin E, Hodaňová K, Huynh-Do U, Kistler A, Morelle J, Papagregoriou G, Pirson Y, Sandford R, Sayer JA, Torra R, Venzin C, Venzin R, Vogt B, Živná M, Greka A, Dahan K, Rampoldi L, Kmoch S, Bleyer AJ Sr, Devuyst O. Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease due to mutations in UMOD and MUC1. Kidney Int. 2020 Sep;98(3):717-731. doi: 10.1016/j.kint.2020.04.038. Epub 2020 May 22. PMID: 32450155.
2019
Subramanian A, Sidhom EH, Emani M, Vernon K, Sahakian N, Zhou Y, Kost-Alimova M, Slyper M, Waldman J, Dionne D, Nguyen LT, Weins A, Marshall JL, Rosenblatt-Rosen O, Regev A, Greka A. Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation. Nat Commun. 2019 Nov 29;10(1):5462. doi: 10.1038/s41467-019-13382-0. PMID: 31784515; PMCID: PMC6884507.
Pablo JL, Greka A. Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases. Trends Pharmacol Sci. 2019 Dec;40(12):911-918. doi: 10.1016/j.tips.2019.10.001. Epub 2019 Nov 5. PMID: 31704171; PMCID: PMC6884692.
Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, Ronco L, Elonga E, Carter TA, Gnirke A, Melanson M, Hartland K, Wieder N, Hsu JC, Deltas C, Hughey R, Bleyer AJ, Kmoch S, Živná M, Barešova V, Kota S, Schlondorff J, Heiman M, Alper SL, Wagner F, Weins A, Golub TR, Lander ES, Greka A. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 2019 Jul 25;178(3):521-535.e23. doi: 10.1016/j.cell.2019.07.002. PMID: 31348885.
Bleyer AJ, Kmoch S, Greka A. Diagnostic Utility of Exome Sequencing for Kidney Disease. N Engl J Med. 2019 May 23;380(21):2080. doi: 10.1056/NEJMc1903250. PMID: 31116938.
2018
Sharma SH, Pablo JL, Montesinos MS, Greka A, Hopkins CR. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159. doi: 10.1016/j.bmcl.2018.12.007. Epub 2018 Dec 4. PMID: 30538066; PMCID: PMC6349029.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. PMID: 30467180; PMCID: PMC6459600.
Živná M, Kidd K, Přistoupilová A, Barešová V, DeFelice M, Blumenstiel B, Harden M, Conlon P, Lavin P, Connaughton DM, Hartmannová H, Hodaňová K, Stránecký V, Vrbacká A, Vyleťal P, Živný J, Votruba M, Sovová J, Hůlková H, Robins V, Perry R, Wenzel A, Beck BB, Seeman T, Viklický O, Rajnochová-Bloudíčková S, Papagregoriou G, Deltas CC, Alper SL, Greka A, Bleyer AJ, Kmoch S. Noninvasive Immunohistochemical Diagnosis and Novel MUC1 Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease. J Am Soc Nephrol. 2018 Sep;29(9):2418-2431. doi: 10.1681/ASN.2018020180. Epub 2018 Jul 2. Erratum in: J Am Soc Nephrol. 2020 Apr;31(4):892. PMID: 29967284; PMCID: PMC6115665.
Christov M, Clark AR, Corbin B, Hakroush S, Rhee EP, Saito H, Brooks D, Hesse E, Bouxsein M, Galjart N, Jung JY, Mundel P, Jüppner H, Weins A, Greka A. Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. JCI Insight. 2018 Feb 22;3(4):e95091. doi: 10.1172/jci.insight.95091. PMID: 29467330; PMCID: PMC5916242.
2017
Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, Greka A. GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death. Cell Chem Biol. 2018 Feb 15;25(2):175-184.e4. doi: 10.1016/j.chembiol.2017.11.006. Epub 2017 Dec 14. PMID: 29249695; PMCID: PMC5819995.
Zhou Y, Castonguay P, Sidhom EH, Clark AR, Dvela-Levitt M, Kim S, Sieber J, Wieder N, Jung JY, Andreeva S, Reichardt J, Dubois F, Hoffmann SC, Basgen JM, Montesinos MS, Weins A, Johnson AC, Lander ES, Garrett MR, Hopkins CR, Greka A. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science. 2017 Dec 8;358(6368):1332-1336. doi: 10.1126/science.aal4178. PMID: 29217578; PMCID: PMC6014699.
Sieber J, Wieder N, Ostrosky-Frid M, Dvela-Levitt M, Aygün O, Udeshi ND, Carr SA, Greka A. Lysine trimethylation regulates 78-kDa glucose-regulated protein proteostasis during endoplasmic reticulum stress. J Biol Chem. 2017 Nov 17;292(46):18878-18885. doi: 10.1074/jbc.M117.797084. Epub 2017 Sep 14. PMID: 28912266; PMCID: PMC5704472.
2016
Buvall L, Wallentin H, Sieber J, Andreeva S, Choi HY, Mundel P, Greka A. Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. J Am Soc Nephrol. 2017 Mar;28(3):837-851. doi: 10.1681/ASN.2016040414. Epub 2016 Sep 14. PMID: 27628902; PMCID: PMC5328162.
Zhou Y, Greka A. Calcium-permeable ion channels in the kidney. Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1157-67. doi: 10.1152/ajprenal.00117.2016. Epub 2016 Mar 30. PMID: 27029425; PMCID: PMC4935772.
Greka A. Human genetics of nephrotic syndrome and the quest for precision medicine. Curr Opin Nephrol Hypertens. 2016 Mar;25(2):138-43. doi: 10.1097/MNH.0000000000000204. PMID: 26808706; PMCID: PMC4752174.
2015
Wieder N, Greka A. Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies. Pediatr Nephrol. 2016 Jul;31(7):1047-54. doi: 10.1007/s00467-015-3224-1. Epub 2015 Oct 21. PMID: 26490951; PMCID: PMC4840088.
Yoon KW, Byun S, Kwon E, Hwang SY, Chu K, Hiraki M, Jo SH, Weins A, Hakroush S, Cebulla A, Sykes DB, Greka A, Mundel P, Fisher DE, Mandinova A, Lee SW. Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53. Science. 2015 Jul 31;349(6247):1261669. doi: 10.1126/science.1261669. PMID: 26228159; PMCID: PMC5215039.
Mundel P, Greka A. Developing therapeutic 'arrows' with the precision of William Tell: the time has come for targeted therapies in kidney disease. Curr Opin Nephrol Hypertens. 2015 Jul;24(4):388-92. doi: 10.1097/MNH.0000000000000137. PMID: 26050127; PMCID: PMC4499164.
2014
Greka A, Weins A, Mundel P. Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2014 Mar 27;370(13):1263-6. doi: 10.1056/NEJMc1400502. PMID: 24670178; PMCID: PMC5176021.
Hoeppner MP, Lundquist A, Pirun M, Meadows JR, Zamani N, Johnson J, Sundström G, Cook A, FitzGerald MG, Swofford R, Mauceli E, Moghadam BT, Greka A, Alföldi J, Abouelleil A, Aftuck L, Bessette D, Berlin A, Brown A, Gearin G, Lui A, Macdonald JP, Priest M, Shea T, Turner-Maier J, Zimmer A, Lander ES, di Palma F, Lindblad-Toh K, Grabherr MG. An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts. PLoS One. 2014 Mar 13;9(3):e91172. doi: 10.1371/journal.pone.0091172. PMID: 24625832; PMCID: PMC3953330.
2013
Buvall L, Rashmi P, Lopez-Rivera E, Andreeva S, Weins A, Wallentin H, Greka A, Mundel P. Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun. 2013;4:2863. doi: 10.1038/ncomms3863. PMID: 24287595; PMCID: PMC4698162.
Schaldecker T, Kim S, Tarabanis C, Tian D, Hakroush S, Castonguay P, Ahn W, Wallentin H, Heid H, Hopkins CR, Lindsley CW, Riccio A, Buvall L, Weins A, Greka A. Inhibition of the TRPC5 ion channel protects the kidney filter. J Clin Invest. 2013 Dec;123(12):5298-309. doi: 10.1172/JCI71165. Epub 2013 Nov 15. PMID: 24231357; PMCID: PMC3859394.
Yu CC, Fornoni A, Weins A, Hakroush S, Maiguel D, Sageshima J, Chen L, Ciancio G, Faridi MH, Behr D, Campbell KN, Chang JM, Chen HC, Oh J, Faul C, Arnaout MA, Fiorina P, Gupta V, Greka A, Burke GW 3rd, Mundel P. Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2013 Dec 19;369(25):2416-23. doi: 10.1056/NEJMoa1304572. Epub 2013 Nov 8. PMID: 24206430; PMCID: PMC3951406.
Greka A, Dekker JP, Calderwood SB. Case 4-2013: A man with acute flank pain. N Engl J Med. 2013 Jun 6;368(23):2237. doi: 10.1056/NEJMc1302635. PMID: 23738559.
Greka A, Bhatia RS, Sabir SH, Dekker JP. Case records of the Massachusetts General Hospital. Case 4-2013. A 50-year-old man with acute flank pain. N Engl J Med. 2013 Jan 31;368(5):466-72. doi: 10.1056/NEJMcpc1201414. Epub 2013 Jan 23. PMID: 23343037.
2012 and earlier
Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schlöndorff J. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. BMC Cell Biol. 2012 Nov 21;13:33. doi: 10.1186/1471-2121-13-33. PMID: 23171048; PMCID: PMC3520717.
Greka A, Mundel P. Calcium regulates podocyte actin dynamics. Semin Nephrol. 2012 Jul;32(4):319-26. doi: 10.1016/j.semnephrol.2012.06.003. PMID: 22958486; PMCID: PMC3581337.
Greka A, Mundel P. Balancing calcium signals through TRPC5 and TRPC6 in podocytes. J Am Soc Nephrol. 2011 Nov;22(11):1969-80. doi: 10.1681/ASN.2011040370. Epub 2011 Oct 6. PMID: 21980113; PMCID: PMC3231779.
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, Pavenstädt H, Hsu HH, Schlondorff J, Ramos A, Greka A. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci Signal. 2010 Oct 26;3(145):ra77. doi: 10.1126/scisignal.2001200. Erratum in: Sci Signal. 2010;3(147):er11. Pavenstaedt, Hermann [corrected to Pavenstädt, Hermann]. PMID: 20978238; PMCID: PMC3071756.
Rhee EP, Souza A, Farrell L, Pollak MR, Lewis GD, Steele DJ, Thadhani R, Clish CB, Greka A, Gerszten RE. Metabolite profiling identifies markers of uremia. J Am Soc Nephrol. 2010 Jun;21(6):1041-1051. doi: 10.1681/ASN.2009111132. Epub 2010 Apr 8. PMID: 20378825; PMCID: PMC2900954.
Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nat Cell Biol. 2004 Aug;6(8):709-20. doi: 10.1038/ncb1150. Epub 2004 Jul 18. PMID: 15258588.
Greka A, Navarro B, Oancea E, Duggan A, Clapham DE. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nat Neurosci. 2003 Aug;6(8):837-45. doi: 10.1038/nn1092. PMID: 12858178.
Oancea E, Bezzerides VJ, Greka A, Clapham DE. Mechanism of persistent protein kinase D1 translocation and activation. Dev Cell. 2003 Apr;4(4):561-74. doi: 10.1016/s1534-5807(03)00087-x. PMID: 12689594.