News
Lab Member Named 2025 Marshall Scholar
We are so proud to announce that Greka Lab / Harvard undergraduate student, John Lin, has been honored with the very prestigious Marshall Scholarship for his graduate studies in the United Kingdom. Congratulations, John!
A VIEW FROM THE FRONTIER | AI FOR SCIENCE FORUM
Siddhartha Mukherjee (Columbia University) leads a conversation with panelists Anna Greka, Anne Vincent-Salomon (Institut Curie), and Dame Janet Thornton (European Bioinformatics Institute) at the AI for Science Forum, hosted by the Royal Society and Google DeepMind.
Connecting the Dots: Biology at Scale in the Age of AI Symposium jointly hosted by the Eric and Wendy Schmidt Center and Ladders to Cures Accelerator
Building on the Broad’s strengths of scaling scientific efforts to accelerate progress, this event facilitated new connections between biologists and AI/ML experts to showcase efforts in scaling mechanisms-focused research in the pursuit of therapeutic discovery for patients with rare diseases and beyond.
Broad Institute Nodal Biology Project featured in AP News
"Some researchers are trying to address the problem scientifically. Dr. Anna Greka said the Broad Institute of MIT and Harvard has launched an effort to look at commonalities behind various conditions — or nodes, which can be likened to branches meeting at a tree trunk. Fixing the nodes with gene therapies or other treatments, rather than particular “misspellings” in DNA responsible for one disorder, could address multiple diseases simultaneously.
“What this does is it increases the number of patients who can benefit from the therapy,” said Greka, a Broad member. “It also makes it infinitely easier or more attractive to anyone, like a biopharmaceutical company, to take the project forward and try to bring it toward the clinic, because they’re going to have a bigger market.”"
We are very proud to announce that Greka Lab member and undergraduate student at Harvard, John Lin, was recently named a Goldwater Scholar as a part of the Barry M. Goldwater Scholarship Program. Congratulations, John!
LAB MEMBER AWARDED HELEN HAY WHITNEY FELLOWSHIP
A big congratulations to Greka Lab postdoctoral fellow, Felichi Mae (Peach) Arines, for receiving the very competitive Helen Hay Whitney Fellowship! We are so proud of you, Peach!
How is AI Helping Revolutionize Disease Research? Anna in conversation with GOOGLE SVP, James Manyika, on the DIALOGUES DISPATCH PODCAST
Broad Institute OF MIT AND HARVARD in collaboration with the termeer foundation PRESENT the 9th annual Rare Disease Day event
“Climbing Ladders to Cures in Rare Disease Research'' took place on Wednesday, February 28, 2024, featuring opening remarks from Jillian Shaw and Belinda Termeer, with talks from Winston Yan, Michelle Rengarajan, Natalie Galant, Jim Geraghty, Kaitlin Samocha, Lukas Lange, Michael Segel, and Sunitha Malepati.
Too many treatable diseases go unnoticed. This could change that.
Washington Post columnist Bina Venkataraman explores the benefits of genetic testing for newborns as a way to prevent the diagnostic odyssey experienced currently by patients and families with rare genetic diseases. The column mentions how Anna is leading an effort to accelerate the discovery of nodal actionable biology in rare genetic diseases.
We are so excited to announce that Anna was a speaker at TED2023. Please stay tuned for the release of her talk on September 28, 2023!
Photo by Kayana Szymczak for STAT
Thank you, Isabella Cueto, of STAT News, for crafting a tremendous profile of Anna, the Greka Lab, and the “molecular sleuthing” we do to advance scientific discoveries for patients. It's a wonderful piece, and definitely makes us feel proud of our team, and of course, Anna!
Broad Institute OF MIT AND HARVARD in collaboration with the termeer foundation PRESENT the 8th annual Rare Disease Day event
“Accelerating Rare Disease Research: Patients as Partners” took place on Monday, February 27, 2023, featuring a program that highlighted both the patient and research perspectives, including remarks from Anna Greka, Belinda Termeer, Vamsi Mootha, Yael Weiss, Daniel Fischer, Tania Simoncelli, Eric Pierce, and a panel discussion focused on partnering with patients to empower progress featuring Samantha Baxter, Charlene Son Rigby, Daniel Fischer, Yael Weiss, Vamsi Mootha, and Tania Simoncelli.
LAB ALUM AWARDED SOROS FELLOWSHIP FOR NEW AMERICANS
We are so proud to announce that Greka Lab alum and MD-PhD student at Stanford University, Esther Elonga, was awarded the Paul & Daisy Soros Fellowship for 2022! Congratulations, Esther! Read more about Esther’s inspirational journey here.
Brigham and Women’s Clinical and Research News features an interview with Anna discussing how curiosity-driven science can benefit patients. Read the full interview here!
On September 14, 2021 the National Academy of Medicine (NAM) announced ten Emerging Leaders in Health and Medicine, including Anna Greka. These scholars have committed to a three-year term working collaboratively across disciplines to advance science, medicine, and promote optimal health for all.
Anna hosts the 7th annual Rare Disease Day event
Rare Disease Day is an international event held on the last day of February to raise awareness about the impact of rare diseases on patients’ lives and to emphasize the need for research. To mark Rare Disease Day, each year the Broad Institute organizes a Focus on Rare Disease Event showcasing rare disease research in our community.
LAB GRADUATE STUDENT NAMED FORBES’ 30 UNDER 30 IN HEALTHCARE
We are thrilled to announce that Greka Lab and Harvard Medical School graduate student, Eriene-Heidi Sidhom, has been selected as one of Forbes’ 30 Under 30 in Healthcare! Congratulations on this incredible accomplishment, Eriene!
Learn more about the investigation of cell-specific disease mechanisms in rare genetic disorder revealing Braf/Mapk as a candidate pathway for the treatment of kidney diseases.
“lAB CHAT: SAVING CELLS FROM KIDNEY DISEASE” Interview with Anna featured in STAT News Morning Rounds
Anna, in conversation with Megan Thielking, discusses the process of kidney cell death in progressive kidney disease and the research around possible interventions.
“UNSTUCK PROTEINS” Article on TMED9 research featured in "In the Pipeline” Science Translational Medicine
"This is a pretty interesting paper on several levels. It sheds light on Mucin I kidney disease (MKD), on protein degradation pathways (a hot topic these days, as those in the industry well know), and it also provides a small molecule lead compound."
“A molecular traffic jam may underlie a rare kidney disease and several other protein misfolding disorders” Article featured in Broad Institute News
"Researchers find that several genetic disorders, including MUC1 kidney disease, may share a novel molecular mechanism — and identify a promising therapeutic lead."
"Chemical Strike against a Dominant-Inherited MUC1-Frameshifted Protein Associated with Progressive Kidney Disease" featured in Trends in Molecular Medicine
"In a recent paper by Dvela-Levitt et al., chemical screening using an immunofluorescent assay identified a compound that caused removal of a dominant-inherited misfolded secretory protein, mucin1-frameshifted, from an intracellular location in immortalized renal epithelial cells of a patient affected with progressive medullary cystic kidney disease."
